Lactoflorene® Cist

Lactoflorene® CIST

Lactoflorene® CIST is a food supplement containing probiotic live lactic acid bacteria, D-mannose from birch and cranberry extract for a healthy urinary tract

Help your well-being with the food supplement containing probiotic live lactic acid bacteria, enriched with D-mannose from birch and Cranberry extract to support the health of your urinary tract

Urinary tract disorders are very common conditions with a higher incidence in women than in men. The reasons are anatomical in that in women the urethra is shorter and it is easier for bacteria in the gut to migrate to the bladder and cause an infection.

Lactoflorene® CIST
T-WIN sachets

PACKS OF 10-20 SACHETS

The T-WIN sachet of Lactoflorene® CIST is divided into two separate compartments, A and B, which prevent the ingredients from interacting with one another until the product is taken, thus guaranteeing optimum preservation of the ingredients and their efficacy.

How to use:
1 T-WIN sachet a day, preferably at bedtime or in the morning on an empty stomach and empty bladder.
For preventive purposes, we recommend cycles of 1 sachet a day, preferably in the morning on an empty stomach and empty bladder, for 10 days per month for at least three consecutive months. On days when you feel uncomfortable take 3 sachets a day for the first two days and 2 sachets a day on the third and fourth days, one in the morning on an empty stomach and the other at bedtime.

Lactoflorene® CISTT-WIN sachets

Symptoms and causes of cystitis

Cystitis has various kinds of symptoms, such as a frequent and painful urge to urinate, difficulty in passing urine, burning that persists even after urination and, at times, with a loss of blood together with the urine or the onset of low-grade fever.
image symptoms and causes of cystitis
One of the main causes of cystitis is the bacterium Escherichia coli, commonly present in the gut. If the bacterial flora becomes altered, this bacterium may proliferate and migrate to the bladder, adhering to its wall and infecting it.
image how to prevent cystitis?

How can cystitis be prevented?

drink at least 2 litres of water per day

spread throughout the day

strictly respect the rules of personal hygiene

and avoid using aggressive soaps and cosmetics

do not hold back urine

when you get the urge to urinate

take products to prevent constipation

which may lead to urinary tract infections

use specific probiotic strains

to maintain the gut balance

The formula of Lactoflorene® Cist

live lactic ferments icon

Live lactic acid bacteria

The probiotic live lactic acid bacterium Lactobacillus paracasei LC11, which promotes a balanced gut flora
cranberry extract icon

Cranberry extract

Cranberry, which is rich in a specific variety of polyphenols, the A-type proanthocyanidins (PACs), aids the functioning of the urinary tract by preventing bacteria from adhering to the urinary epithelium
birch d-mannose icon

D-mannose from birch

D-mannose extracted from birch, which can reduce the migration of bacteria towards the bladder and their adhesion to the urinary epithelium, so that they can be expelled more easily
References

Spaulding CN, et al. Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist Nature 2017. PMID 28614296
Rodrigues DF and Elimelech M. Role of type 1 fimbriae and mannose in the development of Escherichia coli K12 biofilm: from initial cell adhesion to biofilm formation. Biofouling 2009. PMID 19306144
Martinez JJ, et al. Type 1 pilus-mediated bacterial invasion of bladder epithelial cells. EMBO J 2000. PMID 10856226
Nabavi SF, et al. Cranberry for Urinary Tract Infection: From Bench to Bedside. Curr Top Med Chem 2017 – Review. PMID 27572082
Fu Z, et al. Cranberry Reduces the Risk of Urinary Tract Infection Recurrence in Otherwise Healthy Women: A Systematic Review and Meta-Analysis. J Nutr 2017 – Review. PMID 29046404
Gupta K, et al. Cranberry products inhibit adherence of p–fimbriated Escherichia coli to primary cultured bladder and vaginal epithelial cells. J Urol 2007. PMID 17509358
Pak et al., Tamm-Horsfall Protein Binds to Type 1 Fimbriated Escherichia coli and Prevents E. Coli from Binding to Uroplakin Ia and Ib Receptors, J Biol Chem. 2001 Mar 30;276(13): 9924-30.

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